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Lipid Data Analyzer v1.5.2

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尾行 燒錄軟體 玄彬[hr]
商品名稱: Lipid Data Analyzer v1.5.2


商品分類: 3D動畫、模型、模具軟體


商品類型: 3D算法分析軟體


語系版本: 英文正式版


運行平台: Windows XP/Vista/7


更新日期: 2011-07-22




安裝序號:



check crack\serial.txt

英文說明:



The accurate measurement of the lipidome permits insights

into physiological and pathological processes. Of the

present high-throughput technologies, LC-MS especially

bears potential of monitoring quantitative changes in

hundreds of lipids simultaneously. In order to extract

valuable information from huge amount of mass spectrometry

data, the aid of automated, reliable highly sensitive and

specific analysis algorithms is indispensable.



We present here a novel approach for the quantitation of

LC-MS data. The new algorithm obtains its analytical power

by two major innovations: 1) a 3D algorithm that confines

the peak borders in m/z and time direction and 2) the use

of the theoretical isotopic distribution of an analyte as

selection/exclusion criterion. The algorithm is integrated

in the Lipid Data Analyzer (LDA) application, which

additionally provides standardisation, a statistics module

for results analysis, a batch mode for unattended analysis

of several runs and a 3D viewer for the manual

verification.



The statistics module offers sample grouping, tests

between sample groups and export functionalities, where

the results are visualised by heat maps and bar charts.

The presented algorithm has been applied to data from a

controlled experiment and to biological data, containing

analytes distributed over an intensity range of 10^6. Our

approach shows improved sensitivity and an extremely high

positive predictive value compared to existing methods.

Consequently, this application is a valuable improvement

in the high-throughput analysis of lipids.

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作者: oafcrsisv
  (2013-02-22 23:12)
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